Intravenous immunoglobulin in the treatment of drug rash eosinophilia and systemic symptoms caused by phenytoin
A 32 year old Asian female on 300 mg per day of phenytoin following meningioma excision developed a fever with a diffuse maculopapular rash, lymphadenopathy and splenomegaly after12 days.A diagnosis of DRESS (Drug Rash tonic shower cap Eosinophilia and Systemic Symptoms) syndrome was made.Patient was started on prednisolone at a dose of 1 mg/kg but